Edocannabinoid system (ECS)-named for the plant that led to its discovery-is one of the most crucial physiological systems that is involved both in maintaining and establishing human health.

Endocannabinoids and their receptors ARE FOUND IN OUR BODY: in the brain, organs, connective tissues, glands, and immune cells. They are very important due to their complex actions on our nervous system and immune system plus on all of the body’s organs. The mechanism connects brain activity and states of physical health and disease.

These endocannabinoids are the major physiological activators of CB1 and CB2 receptors.

FROM WHERE ENDOCANNABINOID SYSTEM?

Cannabis had been in use for millions of years. Despite records going back more than 4,500 years that document medicinal uses of cannabis, no one knew how it exactly worked until 1964. That year, Yechiel Gaoni and Raphael Mechoulam found out that the main active component of the cannabis plant is tetrahydrocannabinol (THC).

THC, referred to as a “cannabinoid” (like the dozens of other unique components of cannabis – some of the common ones you can see in the photo), acts on the brain, mimicking a key natural player that we have in our body. Since then, the entire natural complex is called “endogenous cannabinoid system,” or “endocannabinoid system” (ECS).

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